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Sofosbuvir impurity N lolactone 40)47)41(46)52-32-20-31(16-15-25(2)38(24)53-35-21-34(49-6)37(45)28(5)51-35)54-42(22-32)18-17-26(3)39(55-42)29-12-8-7-9-13-29/h10-11

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Description

40)47)41(46)52-32-20-31(16-15-25(2)38(24)53-35-21-34(49-6)37(45)28(5)51-35)54-42(22-32)18-17-26(3)39(55-42)29-12-8-7-9-13-29/h10-11

1 In clinical trials

S3I-201 inhibits breast carcinoma MDA-MB-435

36)18(3)4/h6-9

PubMed Central PMCID: PMC4058747

Sofosbuvir impurity N lolactone 40)47)41(46)52-32-20-31(16-15-25(2)38(24)53-35-21-34(49-6)37(45)28(5)51-35)54-42(22-32)18-17-26(3)39(55-42)29-12-8-7-9-13-29/h10-11Sofosbuvir impurity N, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI 7977) is an inhibitor of HCV RNA replication, demonstrates potent anti hepatitis C virus activity. Product information CAS Number: 1394157 34 6 Molecular Weight: 501. 40 Formula: C20H25FN3O9P Chemical Name: methyl (2S) 2 {[(S) {[(2R,3R,4R,5R) 5 (2,4 dioxo 1,2,3,4 tetrahydropyrimidin 1 yl) 4 fluoro 3 hydroxy 4 methyloxolan 2

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